Expression of ErbB3, ErbB4, and neuregulin-1 mRNA during tooth development
نویسندگان
چکیده
منابع مشابه
Alteration in Neuregulin 1/ERbB4 in Absence Epilepsy: Regulatory Effect on TRPV1 Expression
Introduction: The footprint of Neuregulin 1 (NRG1) / ERbB4 in the pathophysiology of some neurological disorders and TRPV1 regulation has been indicated. The alterations in NRG1 and ErbB4 as well as the TRPV1 signaling pathway were investigated during the development of absence epilepsy in the genetic animal model of absence epilepsy. Methods: Male WAG/Rij and Wistar rats were divided into fou...
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Introduction: Complex molecular pathways involve in development of different tissues such as teeth. Differential gene expression patterns during teeth development generates different tooth types. Teeth development results from interactions between oral epithelium and underlying ectomesenchyme cells with neural crest origin. Teeth development are regulated by different signaling networks. In thi...
متن کاملAntipsychotic treatment and neuregulin 1-ErbB4 signalling in schizophrenia.
Evidence from genetic, transgenic and post-mortem studies has strongly supported the critical role that neuregulin 1 (NRG1) and its ErbB4 receptor plays in the pathophysiology of schizophrenia. This article aims to review current evidence regarding the effects of antipsychotic treatment on NRG1-ErbB4 signalling. NRG1 and ErbB4 knockout mice display abnormal behaviours relevant to certain featur...
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The four members of the epidermal growth factor receptor (EGFR/ERBB) family form homo- and heterodimers which mediate ligand-specific regulation of many key cellular processes in normal and cancer tissues. While signaling through the EGFR has been extensively studied on the molecular level, signal transduction through ERBB3/ERBB4 heterodimers is less well understood. Here, we generated isogenic...
متن کاملexpression and localization of neuregulin-1 (nrg1) and erbb2/erbb4 receptors in main endocrine organs of the rhesus monkey
background although neuregulin-1 （nrg1）and its receptors have been indicated at the mrna level in partial human endocrine organs and its functional roles have been evaluated in vitro, their morphological distribution in higher animals are not fully studied. the present research focused on expression of nrg1 and its main receptors erbb2 and erbb4 in main endocrine organs of the rhesus monkey. ma...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2002
ISSN: 1058-8388,1097-0177
DOI: 10.1002/dvdy.10114